Eltrombopag Olamine Oral tablet

What is this medicine?

ELTROMBOPAG (el TROM boe pag) helps your body make more platelets. It is used to treat low platelets caused by chronic immune (idiopathic) thrombocytopenic purpura (ITP) or chronic hepatitis C infection. It is also used in patients with severe aplastic anemia when other medicines have not worked well enough.

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take this medicine on an empty stomach, at least 1 hour before or 2 hours after food. Do not take with food. Avoid antacids, aluminum, calcium, iron, magnesium, selenium, and zinc products for 2 hours before and 4 hours after taking your dose. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor’s advice.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 1 year for selected conditions, precautions do apply.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • changes in vision

  • dark urine

  • general ill feeling or flu-like symptoms

  • light-colored stools

  • loss of appetite

  • right upper belly pain

  • signs and symptoms of a blood clot such as breathing problems; chest pain; severe, sudden headache; pain, swelling, warmth in the leg; trouble speaking; sudden numbness or weakness of the face, arm or leg

  • shortness of breath, chest pain, swelling in a leg

  • unusual bleeding or bruising

  • unusually weak or tired

  • yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • cough

  • diarrhea

  • dry mouth

  • headache

  • muscle aches

  • nausea

What may interact with this medicine?

  • antacids

  • bosentan

  • calcium supplements

  • certain medicines for cholesterol like atorvastatin, fluvastatin, pravastatin, rosuvastatin

  • certain medicines that treat or prevent blood clots like warfarin, enoxaparin, dalteparin, apixaban, dabigatran, and rivaroxaban

  • ezetimibe

  • glyburide

  • imatinib

  • irinotecan

  • iron supplements

  • lapatinib

  • magnesium supplements

  • methotrexate

  • mitoxantrone

  • multivitamins with minerals

  • NSAIDS, medicines for pain and inflammation, like ibuprofen or naproxen

  • olmesartan

  • omeprazole

  • repaglinide

  • rifampin

  • selenium

  • sulfasalazine

  • topotecan

  • valsartan

  • zinc

What if I miss a dose?

If you miss a dose, wait and take your next scheduled dose. Do not take more than 1 dose in 1 day. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • cancer

  • history of blood clots

  • eye disease, vision problems

  • kidney disease

  • liver disease

  • low blood counts, like low white cell, platelet, or red cell counts

  • have had your spleen removed

  • an unusual or allergic reaction to Eltrombopag, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Your condition will be monitored carefully while you are receiving this medicine. To receive this medicine, you, your doctor and your pharmacy must be registered in the Promacta Cares program.

Visit your prescriber or health care professional for regular checks on your progress and for the needed blood tests. It is important to keep all appointments.

Tell your doctor or health care professional right away if you have any change in your eyesight.



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